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Figure 5 | Orphanet Journal of Rare Diseases

Figure 5

From: The diagnosis of inherited metabolic diseases by microarray gene expression profiling

Figure 5

Heat map visualization of pair-wise correlation coefficients and corresponding hierarchical clustering dendrogram. There is some batch effect, with arrays from the same batch tending to cluster. For example, there are distinct clusters comprising only arrays from the grey batch. The clusters do not reflect gender or disease class. Heat map visualization of pair-wise correlation coefficients (r2; left) between arrays and corresponding hierarchical clustering dendrogram (using average linkage and 1-r2 as the distance metric). The branches corresponding to the eight most distinct non-singleton clusters are labeled by asterisks. A cluster was considered distinct if its inconsistency coefficient (IC) was 1.9 at a depth of up to 5.

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