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Table 1 Sub Classification of Platelet Aggregation Defects

From: Bleeding disorders in the tribe: result of consanguineous in breeding

 

ADP

Epinephrine

Collagen

Ristocetin

Epinephrin Receptor Defect,

N

↓

N

N

Glanzman's Thrombasthenia,

↓

↓

↓

N or ↓

Bernard Soulier Syndrome

N

N

N

↓ or Abs

ADP Receptor Defect,

↓

N

N

N

Collagen Receptor Defect.

N

N

↓ or Abs

N

Unclassified

↓ or Abs

↓ or Abs

N

N

  1. ADP- adenosine diphosphate; N - Normal; ↓ - Decrease; Abs - Absent