Table 9 Time course of normalization of serum T4 and TSH with initial l-thyroxine treatment dose (modified from: LaFranchi & Austin. J Pediatr Endocrinol Metab 20:559-578, 2007[80].)
Screening Program | l-thyroxine dose (mcg/kg/day) | Time to serum T4 > 10 ug/dL (days) | Time to serum TSH < 9.1 mU/L (days) |
|---|---|---|---|
Quebec | 6 | 45-90 | Â |
Toronto | 7-9 | 74 | Â |
France | 8 | 15 | 60 |
New England | 10 | 31 | Â |
US (Pennsylvania) | 10-14 | 7 | 150 |
Italy | 10-15 | 30 | 30 |
US (Oregon) | 12-17 | 3 | 14 |