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Table 5 Suggested criteria for non-invasive ventilation (NIV): Provisional European consensus criteria for NIV (European ALS/MND Consortium and European Neuromuscular Centre workshop on non-invasive ventilation in MND, May 2002) [with permission from Leigh et al. 2003]

From: Amyotrophic lateral sclerosis

Symptoms related to respiratory muscle weakness. At least one of
• Dyspnoea
• Orthopnoea
• Disturbed sleep (not caused by pain)
• Morning headache
• Poor concentration
• Anorexia
• Excessive daytime sleepiness (ESS > 9)
AND Evidence of respiratory muscle weakness (FVC ≤ 80% or SNP ≤ 40 cmH2O)
AND Evidence of EITHER:
  significant nocturnal desaturation on overnight oximetry
  OR
  morning ear lobe blood gas pCO2 ≥ 6.5 kPa
  1. ESS, Epworth sleepiness scale