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Table 1 Spigelman classification for duodenal polyposis in FAP

From: Familial adenomatous polyposis

  Stage 1 Stage 2 Stage 3
Polyp number 1-4 5-20 >20
Polyp size (mm) 1-4 5-10 >10
Histology Tubular Tubulovillous Villous
Dysplasia Low grade Low grade High grade
  1. Stage 0, 0 points; stage I, 1-4 points; stage II, 5-6 points; stage III, 7-8 points; stage IV, 9-12 points. Points are accumulated for polyps' number, size, histology and severity of dysplasia. Stage I (1-4 points) indicates mild disease, whereas stage III-IV (7-12 points) implies severe duodenal polyposis. Derived from reference [7].