Table 2 Simulation results of phase IV drop-the-loser design
| Interim sample size per group | Final sample size per group | Probability of identifying the optimal arm |
|---|---|---|
| 25 | 50 | 80.3% |
| 50 | 100 | 91.3% |
| Interim sample size per group | Final sample size per group | Probability of identifying the optimal arm |
|---|---|---|
| 25 | 50 | 80.3% |
| 50 | 100 | 91.3% |
Orphanet Journal of Rare Diseases