Table 1 Genetics of Hereditary Sensory and Autonomic Neuropathies (HSAN)

Hereditary sensory radicular neuropathy

I

AD

9q22.1-22.3

SPTLC1

Congenital sensory neuropathy (CSN)

II

AR

12p13.33

HSN2 (?)

Familial dysautonomia (FD)/Riley Day

III

AR

9q31

IKBKAP

Congenital insensitivity to pain with anhidrosis (CIPA)

IV

AR

1q21-22

NTRK1 (TRKA)

Congenital insensitivity to pain with partial anhidrosis

V

NK

NK

NTRK1

Congenital autonomic dysfunction with universal pain loss (CAD)

NK

NK

Progressive panneuropathy

NK

NK