Table 1 Effect of botulinum toxin on achalasia
Study | Method | Number of patients enrolled | % LES pressure decreased post treatment | Remission rate at 1 months | Remission rate at 6 months | Remission rate at 12 months |
|---|---|---|---|---|---|---|
Pasricha et al, [55] | Randomized control trial | 21 | 33% | 90% | 44% | ___ |
Fishman et al, [56] | Prospective study | 60 | ___ | 70% | ___ | 36% |
Gordon et al, [75] | Prospective study | 16 | ___ | 75% | 48% | ___ |
Vaezi et al, [2] | Randomized trial | 24 | 1% | 60% | 50% | 32% |
Annese et al, [71] | Randomized trial | 16 | 49% | 100% | ___ | 12.5% |
Pasricha et al, [58] | Prospective study | 31 | 45% | 90% | 64% | ___ |
Martinek et al, [76] | Prospective cohort study | 49 | 65% | 93% | ___ | 41% |
Zaninotto et al, [77] | Randomized controlled trial | 40 | ___ | ___ | 66% | 34% |