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Table 3 Medications associated with drug-induced Sweet's syndrome [a-c]

From: Sweet's syndrome – a comprehensive review of an acute febrile neutrophilic dermatosis

Antibiotics

Minocycline [110-112]

 

Nitrofurantoin [113]

 

Norfloxacin [114]

 

Ofloxacin [115]

 

Quinupristin/dalfopristin [118]

 

Trimethoprim-sulfamethoxazole [11,13]

Antiepileptics

Carbemazepine [17]

 

Diazepam [86]

Antihuman immunodeficiency virus drugs

Abacavir (synthetic carbocyclic nucleoside analogue) [69]

Antihypertensives

Hydralazine [107]

Antineoplastics

Bortezomib [d] [78-79]

 

Imatinib mesylate [e] [108,109,401]

 

Lenalidomide [f] [426]

Antipsychotics

Clozapine [82]

Antithyroid hormone synthesis drugs

Propylthiouracil [117]

Colony stimulating factors

Granulocyte-colony stimulating factor [39,41,89-105,398]

 

Granulocyte-macrophage-colony stimulating factor [105,106]

 

Pegfilgrastim [g] [116]

Contraceptives [83]

Levonorgestrel/ethinyl estradiol (Triphasil) [84]

 

Levonorgestrel-releasing intrauterine system (Mirena) [85]

Diuretics

Furosemide [88]

Nonsteroidal anti-inflammatory agents

Celecoxib [80]

 

Diclofenac [87]

Retinoids

All-trans retinoic acid [70-77,417]

 

13-cis-retinoic acid [81,404]

  1. [a] The possibility of acyclovir-induced Sweet's syndrome cannot be completely ruled out in a 13-year-old girl with systemic lupus erythematosus (that had been diagnosed 3 months earlier and was being treated with oral prednisolone and azathioprine) whose Sweet's syndrome lesions appeared 5 days after beginning intravenous acyclovir treatment for a herpes zoster infection [119].
  2. [b] Photodistributed neutrophilic dermatosis with overlapping features of Sweet's syndrome, acute generalized exanthematous pustulosis and sterile neutrophilic folliculitis with perifollicular vasculopathy developed in a patient who had received antidepressant (amoxapine and citalopram) and anxiolytic (perphenazine) therapy [120].
  3. [c] Additional reports have attributed Sweet's syndrome to medications (minocycline [121], furosemide [122], and hydralazine [123,124]); however, they did not fulfill the criteria proposed by Walker and Cohen [13] for drug-induced Sweet's syndrome.
  4. [d] This drug is a reversible inhibitor of the chymotrypsin-like activity of the 26S proteasome in mammalian cells. It is indicated for the treatment of multiple myeloma patients.
  5. [e] This drug is a protein-tyrosine kinase inhibitor that inhibits the bcr-abl tyrosine kinase, the constitutive abnormal tyrosine kinase created by the Philadelphia chromosome abnormality in chronic myeloid leukemia.
  6. [f] This drug is an amino-substituted analogue of thalidomide. It is an immunomodulatory agent with anti-angiogenic and antineoplastic properties. It is indicated for the treatment of: (1) multiple myeloma and (2) transfusion dependent anemia due to low-risk or intermediate-risk myelodysplastic syndromes.
  7. [g] This drug is a covalent conjugate of recombinant methionyl human granulocyte-colony stimulating factor (Filgrastim) and monomethoxypolyethylene.
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Orphanet Journal of Rare Diseases

ISSN: 1750-1172