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Table 2 Main antibodies associated with Paraneoplastic neurological syndromes

From: Paraneoplastic neurological syndromes

Antibodies Main associated neurological syndromes Cancer
Hu-Ab (ANNA1-Ab**) Sensory neuronopathy
Encephalomyelitis
Chronic gastrointestinal pseudoobstruction
Cerebellar ataxia
Limbic encephalitis
SCLC
Yo-Ab (PCA1-Ab**) Subacute cerebellar ataxia Ovary, breast, uterus
CV2-Ab (CRMP5-Ab**) Cerebellar ataxia
Sensory-motor neuropathy
Uveitis, retinopathy
Encephalomyelitis
SCLC, thymoma
Ri-Ab (ANNA2-Ab**) Opsomyoclonus
Cerebellar ataxia
Breast, SCLC
Amphiphysin-Ab Stiff-person syndrome
Sensory neuronopathy
Encephalomyelitis
Breast, SCLC
Tr-Ab Cerebellar ataxia Hodgkin's disease
Ma2-Ab (Ta-Ab**) Limbic encephalitis Testicular
CAR-Ab Retinopathy Breast, SCLC
  1. **Alternative nomenclature which can be found in the literature