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Table 2 Comparison of several features in PNDM and TNDM cases in the French cohort (n = 50) (adapted from [9]).

From: Neonatal diabetes mellitus: a disease linked to multiple mechanisms

 

PNDM n= 21

TNDM n= 29

P value

Gestational age (weeks)

39.2 ± 1.6

38.2 ± 2.2

P = 0.15

Birth weight (g)

2497 ± 690

1987 ± 510

P < 0.006

Birth length (cm)

47.5 ± 2.4

44.3 ± 3.4

P < 0.006

Head circumference (cm)

33 ± 1.9

31.5 ± 1.8

P < 0.02

Intrauterine growth retardation

n = 7/19 36%

n = 20/27 74%

P < 0.03

Median age at diagnosis (days) (range)*

27 (1–127)

6 (1–81)

P < 0.01

Initial insulin dose (unit/kg/day)

1.4 ± 1.2

0.6 ± 0.25

P < 0.006

  1. * Given the non-Gaussian distribution of age in the study population, the nonparametric Mann-Whitney U-test was used to compare age in the two groups.