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Table 2 Clinical evaluation of patient #3 using meloxicam as anti-inflammatory treatment

From: Effective NSAID treatment indicates that hyperprostaglandinism is affecting the clinical severity of childhood hypophosphatasia

 

1. Cycle

2. Cycle

3. Cycle

4. Cycle

after 8 wks

time

before

after

before

after

before

after

before

after

pause

overall well being, physician's global rating

6

9

6

9

5

9

7

8

4

Gower's sign

4

3

5

4

5

3

6

5

6

overall well being, parents' global rating

5

10

5

8

5

9

7

8

5

physical activity

2,2

9,6

3,5

7

1,2

7,5

1,2

2,9

2

fatigue after physical activity

0,5

9,3

1,5

5

2,6

5,4

1,5

5,3

1,5

Gower's sign

2,3

6,4

5

6,4

0,8

2,5

1,2

2,9

1,3

patient wants to be carried

1,2

9,3

3,5

5,5

2,9

7,6

2,5

7,6

2,8

pain in rest

3

7

1,8

7

3,25

9,6

1,6

9,5

1,7

pain after physical activity

1,7

7

3,3

5

1,6

7,3

1,9

6,1

1,5