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Figure 5 | Orphanet Journal of Rare Diseases

Figure 5

From: Effective NSAID treatment indicates that hyperprostaglandinism is affecting the clinical severity of childhood hypophosphatasia

Figure 5

COX-2 gene expression in normal and HP fibroblasts exposed to pyridoxal phosphate (PLP) and/or calcium pyrophosphate (CPPD). Semiquantitative PCR was performed to analyze the expression of the COX 2 gene in normal and HP fibroblasts isolated from the skin and dura mater after exposure to PLP and/or CPPD in vitro. In order to allow comparisons, the expression was normalized to a 100% in each of the three groups of fibroblasts. Statistical analysis was done by 3-way ANOVA.

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Orphanet Journal of Rare Diseases

ISSN: 1750-1172