Table 2 Clinical features of our Chinese cohort compared with Spanish, or German or Indian study

Age (mean ± SD, y)

16.0 ± 9.08

39.6 ± 17.86^a***

NA

13.4 ± 6.42

Age at diagnostic exam(mean ± SD, y)

8.00 ± 7.22

NA

24.49 ± 12.30^a***

NA

Gender (M/F)

11/9

28/24^b

35/26^b

44/20^b

RP, n/N (%)

19/20 (95)

51/52 (98)^c

61/61 (100)^c

62/64(97)^c

OB, n/N (%)

17/20 (85)

44/50 (88)^c

48/61 (79)^c

57/64(89)^c

PD, n/N (%)

19/20 (95)

41/52 (79)^c

53/61 (87)^c

55/64(86)^c

CI, n/N (%)

10/20 (50)

29/49 (59)^b

17/61 (28)^b

42/64(66)^b

Gonad, n/N (%)

15/20 (75)

17/35 (49)^b

6/22(27.3)^b**

42/64(66)^b

RA, n/N (%)

4/18 (22)

12/36 (33)^b

18/61 (30)^b

10/64(16)^c

Development delay

15/20(75)

14/22(64)^b

21/61(34)^b**

31/64(48)^b*

Diabetes

3/18(16.7)

2/64(3)^c

5/61(8)^c

18/64(28)^c

Hearing disturbances

0/19(0)

9/52(17)^c*

2/61(3)^c

14/64(22)^c*

neurology

3/20(15)

14/22(63.6)^b***

18/61(29.5)^b

29/64(45.3)^b*