Overall (N = 64,057) | Male (N = 21,823) | Female (N = 42,234) | |||||||
---|---|---|---|---|---|---|---|---|---|
OR | 95% CI | P value | OR | 95% CI | P value | OR | 95% CI | P value | |
Age (year) | 1.12 | (1.11, 1.12) | < 0.001* | 1.07 | (1.06, 1.07) | < 0.001* | 1.13 | (1.12, 1.14) | < 0.001* |
Gender | 0.66 | (0.62, 0.71) | < 0.001* | – | – | – | – | – | – |
BMI (kg/m2) | 0.91 | (0.91, 0.92) | < 0.001* | 0.92 | (0.91, 0.94) | < 0.001* | 0.89 | (0.88, 0.9) | < 0.001* |
Smoking | 1.16 | (1.09, 1.24) | < 0.001* | 1.34 | (1.23, 1.45) | < 0.001* | – | – | – |
Sport Habit | 0.68 | (0.64, 0.72) | < 0.001* | 0.64 | (0.59, 0.69) | < 0.001* | 0.68 | (0.63, 0.73) | < 0.001* |
Menopause | – | – | – | – | – | – | 2.87 | (2.53, 3.26) | < 0.001* |
eGFR (mL/min/1.73m2) | 1.01 | (1.01, 1.01) | < 0.001* | 1.01 | (1.01, 1.01) | < 0.001* | 1.01 | (1.01, 1.02) | < 0.001* |
rs11264345 | 1.06 | (1.02, 1.11) | 0.002* | 1.10 | (1.04, 1.17) | 0.002* | 1.03 | (0.98, 1.08) | 0.270 |