Rett syndrome in Ireland: a demographic study

Table 6 Representation of the data in the RTT cohort of Ireland and other countries

Characteristic	Mean value within RTT population
Characteristic	US	IT	DK	NL	SE	AU	UK	BR	PL	INTL	IE
Sample size	919	84	27	137	125	349	91	27	23	–	25
Age (years)	3**	29**	40.7**	14.9*	19.6	13.7**	20.5	12.2**	7.22**	–	20.9
Current weight (kg)	–	–	42	–	–	–	–	–	–	–	38
Age at diagnosis (years)	2.5**	–	2*	7.8	–	5.5	3	–	3.5	–	5.25
Age at regression (years)	–	–	–	1**	–	2.6**	1.5	–	–	–	1.66
Age at seizure onset (years)	–	5*	–	4	–	3.4**	–	–	–	–	6.72 Δ

The tabular representation of data such as the current age and weight of the individuals, age of diagnosis, age of regression observed, and age of onset of seizures in the study cohort in Ireland and other international cohorts, such as the USA, Italy, Denmark, Netherlands, Australia, UK, Brazil, and Poland. The ratio of individuals with RTT included in studies from specific countries relative to their overall populations is reported in the methods. The numbers in the figure are accompanied by asterisks to indicate the level of significance of the differences from Ireland (IE). A single asterisk (*) indicates a significant difference from Ireland for the indicated distinctive parameter. The double asterisks (**) indicate a higher level of significance, determined following p-value adjustments for multiple testing. The numbers shown in bold for Ireland indicate an extreme end parameter that has been reported in Ireland and differs greatly from other countries. Instances where the frequency of findings in Ireland is the highest among all other countries are denoted by the symbol "Δ"

ISSN: 1750-1172