Coexistence of meningioma and craniofacial fibrous dysplasia: a case series of clinicopathological study and literature review

Song, Xiaowen; Li, Zhi

doi:10.1186/s13023-024-03032-0

Orphanet Journal of Rare Diseases

Table 2 Detailed clinical information of the 21 patients included in this study

From: Coexistence of meningioma and craniofacial fibrous dysplasia: a case series of clinicopathological study and literature review

No	Age /y	Gender	Onset symptom	Lesion location		Management		Simpson grade	Prognosis
No	Age /y	Gender	Onset symptom	CFD	Meningioma	CFD	Meningioma	Simpson grade	Follow-up/ month	CFD	Meningioma
1	15	Male	Craniofacial deformity	Right maxilla, ethmoid sinus and sphenoid bone	Suprasellar region	Surgery	Surgery	III	80	Unchanged	No recurrence
2	31	Female	Headache	Sphenoid bone	Left parietal-occipital lobe (parafalx)	Watchful waiting	Surgery	I	118	Unchanged	No recurrence
3	39	Female	Hearing loss	Sphenoid bone	Right cerebellopontine angle	Watchful waiting	Surgery	I	57	Unchanged	Recurrence
4	47	Female	Vision loss	Right clivus	Right parasellar region	Watchful waiting	Surgery	II	65	Unchanged	No recurrence
5	54	Female	Vision loss and double vision	Left orbit and frontal bone	Right parasellar region	Watchful waiting	Surgery	I	120	Unchanged	No recurrence
6	58	Male	Seizure	Left maxilla	Left olfactory sulcus	Watchful waiting	Surgery	I	77	Unchanged	No recurrence
7	37	Male	Vision loss	Left frontal bone	Left sphenoid ridge	Surgery	Surgery	II	84	Unchanged	No recurrence
8	37	Female	Headache	Left orbit, frontal, sphenoid and temporal bones	Left tentorium and left frontal lobe (convexity)	Surgery	Surgery	I	12	Unchanged	No recurrence
9	36	Female	Symptom free	Bilateral sphenoid, temporal and occipital bones	Left frontal lobe (parasagittal)	Watchful waiting	Surgery	I	10	Unchanged	No recurrence
10	56	Female	Vision loss	Right temporal bone	Right anterior clinoid process	Watchful waiting	Surgery	I	118	Unchanged	No recurrence
11	61	Female	Dizziness	Left sphenoid	Left frontal lobe (parafalx)	Watchful waiting	Surgery	I	8	Unchanged	No recurrence
12	26	Male	Headache	Bilateral parietal bones	Right petroclival region	Watchful waiting	Surgery	III	24	Unchanged	Recurrence
13	66	Female	Headache	Left sphenoid bone	Posterior part of third ventricle	Watchful waiting	Surgery	II	8	Unchanged	No recurrence
14	51	Female	Double vision	Left frontal–temporal bones	Left cavernous sinus and sphenoid ridge	Surgery	Surgery	II	12	Unchanged	No recurrence
15	38	Female	Headache	Left sphenoid bone	Right lateral ventricle	Watchful waiting	Gamma Knife radiosurgery		24	Unchanged	No progression
16	18	Female	Craniofacial deformity and vision loss	Left frontal bone	Left parasellar region	Watchful waiting	Watchful waiting		72	Unchanged	No progression
17	54	Female	Hearing loss	Right clivus and temporal bone	Right frontal-parietal lobe (convexity)	Watchful waiting	Watchful waiting		36	Unchanged	No progression
18	60	Female	Dizziness	Sphenoid bone and sphenoid sinus	Left lateral ventricle	Watchful waiting	Watchful waiting		72	Unchanged	No progression
19	60	Female	Symptom free	Left sphenoid bone	Left frontal-parietal lobe (parafalx)	Watchful waiting	Watchful waiting		84	Unchanged	No progression
20	61	Female	Symptom free	Left ethmoid sinus	Right petroclival region	Watchful waiting	Watchful waiting		Lost
21	43	Female	Symptom free	Right parietal bone	Right sphenoid ridge	Watchful waiting	Watchful waiting		Lost

CFD cranial fibrous dysplasia, NA not available

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ISSN: 1750-1172

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