Fig. 1

Survey reported frequency of ASMD symptoms before (n = 10) and after (n = 10) treatment with olipudase alfa. Symptom categories are tiredness and fatigue (a), abdominal pain (b), organ enlargement (c), vomiting and nausea (d), bone pain (e), bruising (f), chronic headaches (g), infections over a 6-month period (h), and shortness of breath (i)