Table 1 Characteristics of the patients and of sickle cell related acute events

Patients (% males)

31 (38%)

20 (35%)

9 (56%)

2 (0)

Age (yrs.), mean (SD)

33 (10)

31 (10)

39 (10)

31 (6)

Patients with #1 event

19

13

5

1

Patients with #2 events

9

6

2

1

Patients with #3 events

2

1

1

-

Patients with #5 events

1

-

1

-

Splenectomy or functional asplenia (n)

16

10

6

-

Cholecystectomy

14

10

4

-

HU therapy

22

14

7

1

ICT

8

6

2

-

PPI

20

13

6

1

Number of events

48

28

17

3

Days of ketorolac, mean (SD)

2.6 (1.5)

2.8 (1.6)

2.5 (1.5)

1.3 (0.6)

Previous therapy (%)

26 (54%)

14 (50%)

10 (59%)

2 (67%)

Subsequent hospitalizations (%)

15 (31%)

9 (31%)

5 (29%)

1 (33%)

Hemoglobin (g/dl) baseline

10.1 (1.1)

10.0 (1.1)

10.1 (0.8)

12.0 (0.07)

Hemoglobin (g/dl) acute

9.1 (1.4)

8.8 (1.3)

9.4 (1.5)

11.3 (1.4)

Reticulocyte (10⁹/L) baseline

270 (131)

288 (133)

235 (125)

126

Reticulocyte (10⁹/L) acute

323 (178)

309 (131)

408 (295)

129