Children (N = 22) | Adults (N = 80) | All (N = 102) | ||
---|---|---|---|---|
Leucine level at admission (µmol/L) | N | 22 | 80 | 102 |
Mean (SD) | 900 (267) | 1008 (279) | 985 (279) | |
Median [min; max] | 964 [396; 1304] | 972 [518; 1723] | 972 [396; 1723] | |
Episodes with normalisation of leucine during hospitalisation | ||||
Number of episodes | < 381 μmol/L (< 5 mg/100 mL) | 18 (81.8%) | 67 (83.8%) | 85 (83.3%) |
Leucine level at time of normalisation (µmol/L) | N | 18 | 67 | 85 |
Mean (SD) | 216 (116) | 217 (105) | 217 (107) | |
Median [min; max] | 248 [30; 374] | 213 [23; 381] | 221 [23; 381] | |
% Change from admission | N | 18 | 67 | 85 |
Mean (SD) | − 71 (20.9) | − 76 (14.8) | − 75 (16.2) | |
Median [min; max] | − 75 [− 97; − 22] | − 78 [− 97; − 31] | − 77 [− 97; − 22] | |
Rate of decrease (µmol/L/day) | N | 18 | 67 | 85 |
Mean (SD) | − 267 (146) | − 276 (117) | − 274 (123) | |
Median [min; max] | − 264 [− 526; − 53] | − 267 [− 724; − 50] | − 267 [− 724; − 50] | |
Episodes without any normalisation of leucine during/at end of hospitalisation | ||||
Number of episodes by leucine category (plasma leucine concentration) | 381–762 µmol/L (5–10 mg/100 mL) | 4 (18.2%) | 12 (15.0%) | 16 (15.7%) |
> 762 µmol/L (10 mg/100 mL) | 0 (0.0%) | 1 (1.3%) | 1 (1.0%) |