Prevalence, incidence and carrier frequency of 5q–linked spinal muscular atrophy – a literature review

Table 4 Carrier frequencies for SMA per ethnicity

Population	Number of identified carriers	Number of study participants	Carrier frequency	95% CI
Arab^a	152	9058	0.017	0.014–0.019
Asian	2492	119,718	0.021	0.020–0.022
Asian Indian	20	1465	0.014	0.008–0.020
Black (Sub-Saharan ancestry)	80	8012	0.010	0.008–0.012
Caucasian	680	31,549	0.022	0.020–0.023
Hispanic	127	9649	0.013	0.011–0.015
Jewish	1059	59,196	0.018	0.017–0.019

Median and 95% posterior intervals of SMA carrier frequencies, based on studies presented in Additional file 2. Only ethnicities studied in more than one study are included
CI confidence interval
^a) The isolated Muslim Israeli Arab village [59] has been omitted

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