Skip to main content
Fig. 5 | Orphanet Journal of Rare Diseases

Fig. 5

From: Does the low prevalence affect the sample size of interventional clinical trials of rare diseases? An analysis of data from the aggregate analysis of clinicaltrials.gov

Fig. 5

Fitted mean of sample size and 95% confidence interval back transformed from logarithmic values by class of prevalence and phase of trial adjusted for interaction between prevalence, phase of study and the interaction between prevalence and phase for parallel 2-arm trials only (blue) and single group (1-arm) trials only (brown). Both fitted models were adjusted for other covariates (see Table 5)

Back to article page

Orphanet Journal of Rare Diseases

ISSN: 1750-1172