From: Increased Wnt and Notch signaling: a clue to the renal disease in Schimke immuno-osseous dysplasia?
Patient ID | Unphosphorylated β-catenin expression | Nuclear NICD expression |
---|---|---|
SIOD patients | ||
 SD4b | = | = |
 SD26 | ↑ | ↑ |
 SD60 | ↑ | ↑ |
 SD60 Tx | = | = |
 SD79 | ↑ | = |
 SD120 | ↑ | ↑ |
 SD121 | ↑ | ↑ |
 SD131 | n/aa | ↑ |
 SD146 | ↑ | ↑ |
Isolated FSGS patients | ||
 FSGS-1 | ↑ | = |
 FSGS-2 | ↑ | ↑ |
 FSGS-3 | ↑ | ↑ |
 FSGS-4 | ↑ | ↑ |
 FSGS-5 | ↑ | ↑ |
 FSGS-6 | ↑ | ↑ |
 FSGS-8 | ↑ | ↑ |
 FSGS-9 | ↑ | ↑ |
 FSGS-10 | ↑ | ↑ |