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Table 3 Share (%) of reimbursed ultra-orphan, oncology orphan and other orphan drugs by type of HTA recommendation, by country

From: The correlation between HTA recommendations and reimbursement status of orphan drugs in Europe

 

All orphan (101)

Ultra-orphan

Oncology orphan

Non-ultra, non-oncology orphan drugs

Positive

Conditional

Negative

Not assessed

Positive

Conditional

Negative

Not assessed

Positive

Conditional

Negative

Not assessed

Positive

Conditional

Negative

Not assessed

England

25 %

0 %

14 %

11 %

0 %

0 %

0 %

24 %

33 %

0 %

0 %

0 %

20 %

0 %

50 %

12 %

Germany

76 %

0 %

0 %

1 %

100 %

0 %

0 %

0 %

73 %

0 %

0 %

0 %

77 %

0 %

0 %

3 %

Poland

71 %

69 %

31 %

6 %

100 %

100 %

50 %

27 %

100 %

67 %

38 %

0 %

33 %

57 %

17 %

3 %

Netherlands

20 %

75 %

40 %

10 %

0 %

75 %

100 %

8 %

0 %

83 %

33 %

17 %

33 %

72 %

0 %

7 %

Sweden

100 %

0 %

0 %

0 %

100 %

0 %

0 %

0 %

100 %

0 %

0 %

0 %

100 %

0 %

0 %

0 %

Scotland

19 %

0 %

10 %

5 %

40 %

0 %

20 %

13 %

9 %

0 %

0 %

8 %

19 %

0 %

14 %

0 %

Wales

32 %

0 %

12 %

6 %

60 %

0 %

0 %

20 %

13 %

0 %

10 %

0 %

29 %

0 %

16 %

7 %

France

30 %

0 %

25 %

0 %

18 %

0 %

0 %

0 %

36 %

0 %

0 %

0 %

35 %

0 %

25 %

0 %

All countriesa

49 %

54 %

16 %

5 %

53 %

67 %

19 %

11 %

46 %

41 %

14 %

4 %

49 %

57 %

17 %

5 %

  1. Source: Authors based on information from the websites of the eight HTA agencies; a calculated as the sum of all reimbursed drugs with particular type of recommendation (positive/conditional/negative/no recommendation) from all agencies divided by the sum of all drugs (reimbursed and not reimbursed) with particular type of recommendation from all agencies