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Table 2 Baseline and follow up PSG data in children with suspected ROHHAD

From: ROHHAD syndrome and evolution of sleep disordered breathing

Baseline PSG

Follow-up PSG

Pt

BMI (kg/m2)

Age (years)

PSG Diagnosis

SaO2 Min (%)

Co2 range (mmHg)

Treatment

• Time interval (years)

• N of PSG

BMI (kg/m2)

PSG diagnosis

CO2 range (mmHg)

Treatment

1

35.7

4.7

Mild OSA

79

41–47

Weight loss

• 1y 4 m

43.5

Severe OSA and NH

50–54

• Bi-Level PAP

• OAHI 3/h

• CAI 0/h

• 5

• OAHI 12/h

• CAI 0/h

 

• Suppl. Oxygen (day)

2

28.5

9.0

Mild OSA

82

41–49

Weight loss

• 2y 5 m

36.4

Moderate OSA and NH

35–52

Bi-Level PAP

• OAHI 4/h

• CAI 0/h

• 3

• OAHI 9/h

• CAI 0/h

3

26.5

10.1

Severe OSA

83

29–38

•Adenotonsillectomy

• Weight loss

• 6 m

26.6

Severe OSA and NH

40–53

• Bi-Level PAP

• OAHI 49/h

• CAI 0/h

 

• 1

• OAHI 142/h

• CAI 2.9/h

• Oxygen (day and night)

4

40.7

8.3

NH

90

47–60

Bi-Level PAP

• 8 m

40.4

No change

#32–39

Maintained on Bi-Level PAP

• OAHI 0/h

• CAI 0/h

• 1

• OAHI 0/h

• CAI 0/h

5

40.8

5.3

Severe OSA and NH

67

50–86

Bi-Level PAP

-

-

• NOT PERFORMED

-

-

• OAHI 11/h

• CAI 0/h

• Pt deceased

6

39.9

10.0

Mild OSA

81

38–44

Weight loss

• 4y 8 m

47.6

Severe OSA and NH

Peak 51

Bi-Level PAP

• OAHI 4/h

• CAI 0/h

• 8

• OAHI 18/h

• CAI 0/h

  1. Time Interval describes the time between the first and follow-up PSG in the table; Number of PSG refers to the total number of PSG that were performed between the first PSG and the follow-up PSG in the table; # - patient number 4 was not hypercapnic on follow-up PSG as this was undertaken on Bi-Level PAP
  2. Abbreviations: OSA obstructive sleep apnea, NH nocturnal hypoventilation, OAHI obstructive apnea hypopnea index, CAI central apnea index, AT adenotonsillectomy