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Table 1 Activity of the three complement pathways in the three patients and their parents

From: Invasive meningococcal disease in three siblings with hereditary deficiency of the 8th component of complement: evidence for the importance of an early diagnosis

 

Classical pathway

Alternative pathway

Lectin pathway

%

%

%

Patient 1

0

0

0

Patient 2

3

0

0

Patient 3

3

0

0

Mother

116

92

120

Father

122

91

125

Normal range

69–129

30–113

0–125