Table 2 Demographic parameters of MEFV mutation-negative FMF patients
From: Familial Mediterranean fever without MEFV mutations: a case–control study
Mutation-negative (N = 47) | Heterogeneous controls (N = 60) | P value * | p.M694V homozygous (N = 57) | P value # | |
|---|---|---|---|---|---|
Females (%) | 31 (65.9%) | 30 (50%) | 0.117 | 36 (63.2%) | 0.838 |
Age of disease onset (yrs) | 19.61 ± 15.3 | 12.35 ± 10.36 | 0.011 | 5.76 ± 6.4 | 0.0001 |
Average diagnosis delay (yrs) | 9.95 ± 11.2 | 6.91 ± 8 | 0.373 | 7.59 ± 9.5 | 0.234 |
Positive family history of FMF | 21 (44%) | 44 (73.3%) | 0.003 | 45 (78.9%) | 0.0005 |