Table 3 Treatment Modalities of Infantile BP Patients

Topical corticosteroids alone

N = 8 (9.9%)

Good response

Topical corticosteroids + IVIG

N = 1 (1.2%)

Several relapses for one year

Topical corticosteroids + erythromycin

N = 1 (1.2%)

Good response

Systemic +/− topical corticosteroids (+/− antibiotics)

N = 41 (50.6%)

Good response

Systemic corticosteroids + dapsone/ sulphapyridin (+/− antibiotics)

N = 16 (19.8%)

Good response

Dapsone/ sulphapyridin alone

N = 2 (2.5%)

One relapse under treatment. Same treatment was attempted in one other patient without success, so steroids were added.

No treatment

N = 1

N/A

N = 1

Corticosteroids +/− dapsone plus other medications due to poor response

N = 11 (13.7%)

• Azathioprine

N = 1

No response

• Cyclosporine

N = 2

Good response in N = 1 Partial response in N = 1

• Mycophenolate mofetil

N = 7

Moderate response in N = 7

• Erythromycin and nicotinamide

N = 8

Good response in N = 3 Partial / uncertain response in N = 5

• IVIG

N = 8

Good response in N = 2 Partial/ uncertain response in N = 6

• Rituximab

N = 3

Good response N = 2. Partial response N = 1. One sudden death in one of those two patients after three months (child had congenital immune deficiency).

• Omalizumab

N = 1

Good response