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Figure 4 | Orphanet Journal of Rare Diseases

Figure 4

From: Niemann-Pick disease type C clinical database: cognitive and coordination deficits are early disease indicators

Figure 4

Manifestation of 10 characteristic neurological NP-C signs relative to diagnosis. Sequence of occurrence of 10 selected neurological symptoms with diagnostic importance (acc. to Wijburg et al., 2012, [8]), normalized to the relative age at diagnosis (y=0). Each dot represents one patient. Medians are indicated by grey bars. Symptoms are aligned in order of appearance (bottom to top). VSGP, vertical supranuclear gaze palsy.

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Orphanet Journal of Rare Diseases

ISSN: 1750-1172