Figure 3From: Niemann-Pick disease type C clinical database: cognitive and coordination deficits are early disease indicatorsSequence of most frequent neuropsychiatric symptoms during disease course. Estimated median time until presentation (±95%CI) of the 21 most frequent neurological signs present in >40% of studied neurological patients (n=38), normalized to the relative age at neurological disease onset (x=0). Symptoms are aligned in order of appearance (bottom to top). VSGP, vertical supranuclear gaze palsy.Back to article page